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Cancer Prevention & Control News and Announcements

LunchLearnLink: April 10 Webcast

LunchLearnLink seminars are now available by webcast while the seminar is in progress. To join our discussion, click on "For more information" below. If you have trouble, call Kay Castleberry at 410-955-3720. Real Player is required to view slides and hear lecture. To download a free copy of RealPlayer, go to www.real.com.

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$3 Million in AACR Grants and Fellowships Available

The Jeannik M. Littlefield-AACR Grants in Metastatic Colon Cancer Research These grants provide between $500,000 - $1,000,000. The AACR will award 2-4 grants in 2008. Application Deadline: February 1, 2008 Landon Foundation-AACR INNOVATOR Award for International Collaboration Prestigious $100,000 two-year grant to support an established international cancer research collaboration between two or more principal investigators anywhere in the world. Application deadline: February 15, 2008 Landon Foundation-AACR INNOVATOR Award for Cancer Prevention Research A two-year grant of $100,000 for an outstanding early-career Assistant Professor. Submission Deadline: February 15, 2008 AACR Centennial Postdoctoral Research Fellowships in Cancer Research: $60,000 per year for up to three years to provide salary support and research funding for clinical and postdoctoral fellows. Application deadline: February 1, 2008 AACR Centennial Pre-doctoral Research Fellowships in Cancer: $30,000 per year over a maximum period of three years will be awarded for salary support and research funding. Application deadline: February 1, 2008 AACR-AstraZeneca-Prevent Cancer Foundation Fellowship for Translational Lung Cancer Research: A three-year grant of $90,000. Extended Submission Deadline: February 1, 2008. AACR-Pancreatic Cancer Action Network Fellowship for Pancreatic Cancer Research, in memory of Samuel Stroum: One-year grant of $45,000. Open to investigators at US institutions only. Extended Submission Deadline: February 1, 2008. AACR-Genentech BioOncology Fellowship for Cancer Research in Angiogenesis: Two-year grant of $70,000 for the salary and benefits of the Fellow. Open to investigators at US institutions only; candidates must hold an M.D. or combined M.D./Ph.D. Extended Submission Deadline: February 1, 2008. AACR-Colorectal Cancer Coalition Fellows Grant, in memory of Lisa Dubow: One-year grant of $30,000. Research projects are restricted to translational or clinical cancer research. Extended Submission Deadline: February 1, 2008. AACR-FNAB Fellows Grant for Translational Pancreatic Cancer Research: One-year grant of $35,000. Proposed research must have implications for individualized cancer treatment and make use of human biopsies or samples, such as needle biopsies or circulating cancer cells. In vivo primary tumor explants meet these criteria, but xenografts from established cell lines do not. Extended Submission Deadline: February 1, 2008. AACR-Genentech BioOncology Career Development Award for Cancer Research on the HER Family Pathway: Two-year grant of $100,000. Extended Submission Deadline: February 1, 2008.

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HOWARD/HOPKINS PARTNERSHIP 2008 FULL PROJECT AND PILOT PROJECT INITIATIVE

The Howard University Cancer Center (HUCC) and the Johns Hopkins Sidney Kimmel Cancer Center (SKCCC) have established a Partnership to enhance the research, training, outreach, and education missions of both Institutions. As part of the partnership, joint research projects, both full projects and pilot projects, between SKCCC and HUCC investigators are supported. New projects are identified and targeted regularly for strategic funding. In addition, joint efforts in education and training are also undertaken. This year, the partnership is soliciting for both full projects and pilot projects to support new collaborative Howard/Hopkins projects. Biologic, clinical, and population-based projects studying important issues related to health disparities will be considered. Priority will be given to new partnerships.

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The American Association for Cancer Research Accepting Aplications for Two Fellowships and One Major

AACR Centennial Postdoctoral Research Fellowships in Cancer Research AACR Centennial Postdoctoral Research Fellowships in Cancer Research will provide $60,000 per year for up to three years to provide salary support and research funding for clinical and postdoctoral fellows in the first, second, or third year of their fellowship status. In addition to financial flexibility these fellowships also provide career flexibility. Fellowship funds may be transferred to move with the grantee if the grantee's fellowship is completed during the grant term - a valuable commodity for a newly-independent investigator. AACR Centennial Pre-doctoral Research Fellowships in Cancer The AACR Centennial Pre-doctoral Research Fellowships in Cancer Research will provide full-time graduate students a rare opportunity to invest in their future cancer research careers. The grant terms are flexible, allowing applicants to tailor their grant funds to fit their individual research funding and salary needs. Grantees may also transfer their funds to a postdoctoral fellowship position, should they advance in their careers during grant term. A grant of $30,000 per year over a maximum period of three years will be awarded for salary support and research funding. Littlefield-AACR Grants for Metastatic Colon Cancer Research The Littlefield-AACR Grants for Metastatic Colon Cancer Research support innovative cancer research projects designed to improve the survival and quality of life of patients with metastatic colorectal cancer. Such projects must lead to individualized therapeutic options for treatment or development of promising new cancer therapeutics for metastatic colon cancer which will translate into clinical applications within a one- to two-year period. Due to the intent to support projects on an accelerated track into the clinic, special emphasis will be placed on those where Phase I clinical trials have been successfully conducted. These grants will be provided in an amount between $500,000 - $1,000,000. The AACR will award 2-4 grants in 2008. Inquiries may be directed to awards@aacr.org.

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GENOME UPDATE DEFINES LANDSCAPE OF BREAST AND COLON CANCERS

One year after completing the first large-scale report sequencing breast and colon cancer genes, Johns Hopkins Kimmel Cancer Center scientists have studied the vast majority of protein-coding genes which now suggest a landscape dominated by genes that each are mutated in relatively few cancers. Their report indicates that while little is known about these less-commonly mutated genes, they can be grouped into clusters according to their pathways.

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HOPKINS STUDENT WINS TOP PRIZE FOR CANCER THERAPY INTERVENTION

A postgraduate student at the Johns Hopkins Kimmel Cancer Center has won top prize in a national inventors competition for a new combo approach to kill cancer using bacteria and drug-filled molecular capsules. Ian Cheong, Ph.D., is the grand prize winner of the 2007 Collegiate Inventors Competition hosted by the National Inventors Hall of Fame. The award was announced November 1 at the California Institute of Technology campus where Cheong and 10 other finalists presented their inventions to a panel of eight judges, including several Hall of Fame inductees. Along with the award, Cheong will receive a $25,000 cash prize and $15,000 will go to his adviser, cancer researcher Bert Vogelstein, M.D.

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NEW RADIOACTIVE AGENTS FOR COLON CANCER WORK INSIDE CELLS

Johns Hopkins scientists have developed a potentially novel way to fight colorectal cancer using tiny molecules to deliver potent barrages of radiation inside cancer cells, unlike current treatments that bind to the surface of cells and attack from the outside and cause unwanted side effects.

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BROCCOLI SPROUT-DERIVED EXTRACT PROTECTS AGAINST ULTRAVIOLET RADIATION

A team of Johns Hopkins scientists reports in the Proceedings of the National Academy of Sciences that humans can be protected against the damaging effects of ultraviolet (UV) radiation -- the most abundant cancer-causing agent in our environment -- by topical application of an extract of broccoli sprouts.

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Cancer Genoma Atlas Data Portal

The National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI) would like to advise you of the availability of the -initial version of The Cancer Genome Atlas (TCGA) Data Portal. The Data Portal serves as a storage and data management tool for TCGA data. All genomic characterization, sequencing and clinical data from TCGA are available within the Portal. The Data Portal makes accessible the first of many sets of data from TCGA, and will be continually updated as data are generated. Please check back frequently for updates, additional data submissions, and improvements to the functionality of the database. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. This 3-year pilot project was announced in December of 2005, and after careful planning, the first funding awards were made in the Fall of 2006.

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EXPERIMENTAL ANTI-CANCER DRUG MADE FROM CORN LILLIES KILLS BRAIN TUMOR STEM CELLS

A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.

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Funding Opportunities

American Cancer Society Funding for PH Faculty, Students (Multiple Due Dates) The research program at the American Cancer Society focuses on beginning investigators, a program of targeted research and an enhanced commitment to psychosocial and behavioral, health services, health policy, epidemiological, clinical and cancer control research. In response to identified needs in clinical oncology, the Society also sponsors grants in support of training for health professionals seeking to develop their clinical expertise and/or their ability to conduct independent research.

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Funding Opportunities for ASPH Member Schools

The Association for Schools of Public Health (ASPH) regularly provides information about grant opportunities. A full listing of grants notices can be found by visiting the Funding for Faculty section of the ASPH Web site.

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Cancer Surveillance Information Resource for Marylanders

The Maryland Department of Health and Mental Hygiene has developed a new website to provide online information on Maryland-specific cancer information. The website offers easy access to the latest information on a wide-range of cancer surveillance issues.

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